Materials
Stains on a mattress
A mattress does not go in the wash. Blot, treat thinly, and dry with a fan — leftover damp becomes mildew. Blood and sweat are the usual guests.
More stains on mattress
BloodMattress
Blood on a Mattress — How to Get It Out
Blood stains on a mattress come out best when you treat them quickly with cold water and enzyme soap, then lift any remaining color with hydrogen peroxide. Never use hot water on blood — heat sets the protein permanently. Because you can't throw a mattress in the washing machine, you'll work in layers: blot, treat, rinse without soaking the padding, and air-dry thoroughly to prevent mold.
SweatMattress
Sweat Stains on a Mattress — How to Get Them Out
Sweat stains on a mattress respond well to a paste of baking soda, hydrogen peroxide, and dish soap, which lifts the discoloration and neutralizes odor without soaking the foam or springs. Because you can't throw a mattress in the washer, you'll work on the surface and let it air-dry completely before making the bed again.